Drugs & Vitamins

Ondansetron Oral Solution Active Ingredients: Ondansetron Oral Solution Representative Names: Zofran solution What are ondansetron oral solutions? What should I tell my health care provider before I take this medicine? How should I take this medicine? What if I miss a dose? What drug(s) may interact with ondansetron? What side effects may I notice from taking ondansetron? What should I watch for while taking ondansetron? Where can I keep my medicine? What are ondansetron oral solutions? (Back to top) ONDANSETRON (Zofran® oral solution) helps to relieve nausea and vomiting, especially when associated with the treatment of cancer (chemotherapy). Ondansetron may also be used to prevent or treat nausea and vomiting that occurs after surgery, and occasionally is used to treat severe vomiting during pregnancy. Generic ondansetron oral solution is available. What should I tell my health care provider before I take this medicine? (Back to top) They need to know if you have any of these conditions: •liver disease •an unusual or allergic reaction to ondansetron, granisetron, other medicines, foods, dyes, or preservatives •pregnant or trying to get pregnant •breast-feeding How should I take this medicine? (Back to top) Ondansetron oral solution is taken by mouth (swallowed). Follow the directions on your prescription label. Use a specially marked spoon or container to measure your medicine. Ask your pharmacist if you do not have one; household spoons are not always accurate. Take your doses at regular intervals. Do not take your medicine more often than directed. If you are taking ondansetron to prevent nausea due to chemotherapy, the first dose of ondansetron is usually given 30 minutes before chemotherapy, followed by a dose at regular intervals for one or two days after chemotherapy. Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed. What if I miss a dose? (Back to top) If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses. What drug(s) may interact with ondansetron? (Back to top) •bosentan •carbamazepine •cisplatin •cyclophosphamide •phenobarbital •phenytoin •rifabutin •rifampin •rifapentine •St. John's wort •tramadol Tell your prescriber or health care professional about all other medicines you are taking, including non-prescription medicines, nutritional supplements, or herbal products. Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. Check with your health care professional before stopping or starting any of your medicines. What side effects may I notice from taking ondansetron? (Back to top) Side effects that you should report to your prescriber or health care professional as soon as possible: •difficulty breathing, wheezing, shortness of breath •fast or irregular heartbeat •fever and chills •tightness in the chest •skin rash, itching •swelling of the face, tongue, throat, hands and feet Side effects that usually do not require medical attention (report to your prescriber or health care professional if they continue or are bothersome): •constipation or diarrhea •dry mouth •fainting or lightheadedness •headache •stomach pain •tiredness What should I watch for while taking ondansetron? (Back to top) Check with your prescriber or health care professional as soon as you can if you have any sign of an allergic reaction. Do not take alcohol while taking ondansetron. Where can I keep my medicine? (Back to top) Keep out of the reach of children. Store between 2 and 30 degrees C (36 and 86 degrees F). Protect from light. Throw away any unused medicine after the expiration date. Last Updated:01/04/2007 CLINICAL PHARMACOLOGY© GOLD STANDARD MULTIMEDIA INC, ALL RIGHTS RESERVED

Note: The above information is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist, or other healthcare professional. It should not be construed to indicate that the use of the product is safe, appropriate, or effective for you. Consult your healthcare professional before taking the product.